Aims
To assess the prevalence of GIM and its associated risk factors among patients who undergoing upper endoscopy procedures or gastric resection at King Abdulaziz University Hospital, in the western region of Saudi Arabia
Methods
This retrospective study included 2,103 patients who underwent upper endoscopy or gastric resection at a tertiary facility. Data on patient demographics, risk factors, procedural indications and tissue sampling were collected and analyzed.
Results
GIM was identified in 119 patients (5.7%) who had significantly higher mean age (55.83±15.88 years, P value<0.001) compared to the non-GIM group. Among all patients, 547 had H-pylori infection. Coexisting dysplasia was present in 42 patients and cancer was detected in 46 patients. H-pylori positivity was significantly higher in the GIM group (P value<0.001). Additionally, the GIM group showed a significantly higher prevalence of cancer and dysplasia (p-value of 0.001 for both).
Conclusions
A significantly higher proportion of patients with GIM had coexisting gastric cancer and dysplasia. Advanced age and H-pylori were strongly associated with GIM. Our findings support the well-established link between H-pylori infection and the increased risk of dysplasia and cancer progression.