Standard endoscopic ultrasound-guided biopsy procedures (FNB) for sampling gastrointestinal tract solid tumors have become routine practice, but a histological diagnosis is not always possible, and multiple needle passes are often required to obtain an adequate sample for analysis.A new motorized EUS-guided biopsy device has recently become available. Our institution was among first four centers worldwide that had the opportunity to test it.

At Sestre milosrdnice University Hospital Centre, six patients have undergone biopsy with this method so far. Basic education on how to operate the device was done on-site by the manufacturer.Biopsies were obtained using a flexible, electrically powered, high-speed rotating device equipped with a 17G needle that collects samples through controlled passes across targeted lesions.Nurses play a key role in ensuring the procedure is performed safely and efficiently. Responsibilities of nurses include preparing the endoscopy room, checking the functionality of the EUS equipment, preparing the biopsy system, and maintaining sterile conditions. Before the procedure, the nurse participates in informing the patient, verifies documentation, and ensures that informed consent has been signed.During the biopsy procedures the nurse assists the physician, monitors the patients’ vital signs, and ensures timely preparation and delivery of the required instruments. After the procedure, the nurse monitors the patient during recovery, observes potential immediate complications, and documents all relevant information regarding the procedure and the patients’ condition.

In all six patients, the first and only EUS-guided tissue acquisition pass was sufficient to obtain diagnostic tissue.The only adverse event was mild bleeding in one patient, which was successfully stopped endoscopically and did not require blood transfusion.All patients underwent the procedure under anesthesia.Investing in nurses education for EUS-guided biopsy procedures increases patient safety, improves sample quality, and contributes to a more efficient diagnostic process.

The nurse is a key link connecting the technical demands of the procedure with patient care and safety.Overall, initial experience with this new motorized EUS device was positive. Advantages include a higher likelihood of obtaining an adequate sample, which ultimately results in fewer repeated procedures, less discomfort for the patient, and lower overall diagnostic costs.