Abstract Text
Choledocholithiasis after Roux-en-Y gastric bypass poses major endoscopic challenges. When enteroscopy fails, EUS-guided options are often unfeasible: EDGE is not possible, EDEE is unpredictable, and EUS-BD lacks intrahepatic dilation. We report a single-session rendezvous using the gallbladder as an access port. After failed ERCP, EDEE, and EUS-BD, a Spaxus cholecysto-jejunostomy enabled cholecystoscopy and transcystic guidewire passage to the duodenum. Saline instillation allowed creation of a 20×10-mm Axios jejuno-duodenostomy, granting gastroscopic access to the papilla. Sphincterotomy, stone extraction, and temporary covered stent placement restored biliary drainage, resolving symptoms. The gallbladder offers a feasible endoscopic route to perform ERCP in altered anatomy when standard strategies fail.