1) Evaluate the effectiveness of snare tip Coagulation Spray in the treatment of radiation proctopathy.

2) Evaluate adverse events (AEs) related to the procedure, including pain, bleeding, and strictures, and the number of sessions required to achieve clinical effectiveness.

This retrospective study was conducted at Instituto do Câncer do Estado de São Paulo between January and December 2024.

Inclusion criteria were patients over 18 years old with a confirmed diagnosis of chronic radiation proctopathy and rectal bleeding.

Exclusion criteria included severe coagulopathies, inadequate bowel preparation, or incomplete data.

Data were obtained from electronic medical records. Technical success was defined as achieving complete hemostasis without the need for additional techniques. Clinical efficacy was determined by the absence of bleeding within 30 days after the procedure. Adverse events were categorized as early (≤48 hours) or late (>48 hours).

Eighteen patients were included. The total number of sessions was 32. Two patients died due to oncological comorbidities. Of the 16 patients analyzed, 7 patients (43.8%) underwent two sessions, 6 patients (37.5%) one session, 2 patients (12.5%) three sessions, and 1 patient (6.2%) received four sessions to achieve complete hemostasis.

Technical success was 100%, and clinical success was 87,5%. Non-adverse events were recorded.

Non-contact monopolar coagulation spray using a snare tip, is a safe and effective treatment for chronic radiation proctopathy. With a high technical and clinical success rate and an absence of associated adverse events. Coagulation Spray represents a viable and economical alternative to argon plasma coagulation, especially in resource-limited settings.