In patients with refractory reflux disease and gastric inlet patches ablation with Argon plasma coagulation (APC) is an established therapeutic tool. The goal is to destroy selectively ectopic mucosa to reduce acid production and improve thereby symptoms and quality of life. But precise application of APC is challenging in the upper esophagus. Aim of the study was to evaluate the feasibility of a novel cap for APC (ArgoCap).

21 patients (m,f) were treated for gastric inlet patches using a novel transparent cap attached to the tip of the gastroscope which allows for angled positioning of the APC probe (ArgoCap). APC mode was 20W, precise mode. Feasibility, Clinical success and satisfaction with the examination was assessed. Additionnally clinical data on reflux symptoms before and after treatment in short time surveillance, complications and adverse events were assessed.

APC therapy using the ArgoCap was feasible and technically successful in 100% of all cases. No complications or adverse events were reported. The investigators rated the cap's use as easy to perform.

Precise APC therapy using the ArgoCap in the esophagus is feasible and easy to perform for treatment of gastric inlet patches. Further studies are mandatory to analyse the impact on clinical long-term success of the therapy.